Publications
2025
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Abbadi A, Eklund M, Aly M, Clements M, Crippa A, Discacciati A, Björklund A, Lanka V, Micoli C, Lantz A, Grönberg H, Nordström T. Data Resource Profile: STHLM0, the Stockholm Prostate Cancer Diagnostics Register. International Journal of Epidemiology, Volume 54, Issue 3, June 2025, dyaf062.
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Dembrower KE, Crippa A, Eklund M, Strand F. Prognostic Value of the Circulating Tumor DNA Fraction in Metastatic Castration-resistant Prostate Cancer: Results from the ProBio Platform Trial. European Urology Oncology. 2025 Apr 21.
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Crippa A, De Laere B, Discacciati A, Larsson B, Persson M, Johansson S, D’hondt S, Hjälm-Eriksson M, Pettersson L, Enblad G, Ullén A, et al. Human-AI Interaction in the ScreenTrustCAD Trial: Recall Proportion and Positive Predictive Value Related to Screening Mammograms Flagged by AI CAD versus a Human Reader. Radiology. 2025 Mar 18;314(3):e242566.
2024
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Hammarström M, Gabrielson M, Bergqvist J, Lundholm C, Crippa A, Bäcklund M, Wengström Y, Borgquist S, Eliasson E, Eriksson M, Tapia J, et al. Influence of endoxifen on mammographic density—results from the KARISMA trial. JNCI: Journal of the National Cancer Institute. 2024 Nov 8:djae280.
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De Laere, B.*, Crippa A*, Discacciati A, Larsson B, Persson M, Johansson S, D’hondt S, Bergström R, Chellappa V, Mayrhofer M, Banijamali M, et al. Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial. Nature Medicine. 2024 Aug 20:1-2 https://doi.org/10.1038/s41591-024-03204-2.
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Cruz-Sanabria F, Bruno S, Crippa A, Frumento P, Scarselli M, Skene DJ, Faraguna U. Optimizing the Time and Dose of Melatonin as a Sleep-Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose-Response Meta-Analysis. Journal of pineal research. 2024 Aug;76(5):e12985.
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Klein T, Breilmann J, Schneider C, Girlanda F, Fiedler I, Dawson S, Crippa A, Priebe S, Barbui C, Becker T, Kösters M. Dose-response relationship in cognitive behavioral therapy for depression: A nonlinear metaregression analysis. Journal of Consulting and Clinical Psychology. 2024 May;92(5):296.
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Sabé M, Hyde J, Cramer C, Eberhard A, Crippa A A, Brunoni AR, Aleman A, Kaiser S, Baldwin DS, Garner M, Sentissi O. Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation Across Mental Disorders: A Systematic Review and Dose-Response Meta-Analysis. JAMA Network Open. 2024 May 1;7(5):e2412616.
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Mayrhofer M, Bergstrom R, Chelappa V, Kotsalaynen A, Murugan SK, Crippa A, Laere BD, Urtishak K, Dalsgaard Sorensen K, Garg K, Singh U. Sensitive detection of copy number alterations in samples with low circulating tumor DNA fraction. medRxiv. 2024:2024-05.
2023
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Lehner F, Crippa A, Sigg S, Eberli D, Mortezavi A. Transperineal template saturation and conventional biopsy for stage prediction in prostate cancer. BJU Int. 2023 Sep 13. doi: 10.1111/bju.16181
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Dembrower K, Crippa A, Colón E, Eklund M, Strand F. ScreenTrustCAD Trial Consortium. Artificial intelligence for breast cancer detection in screening mammography in Sweden: a prospective, population-based, paired-reader, non-inferiority study. Lancet Digit Health. 2023 Sep 8:S2589-7500(23)00153-X. doi: 10.1016/S2589-7500(23)00153-X
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Hammarström M, Gabrielson M, Crippa A, Discacciati A, Eklund M, Lundholm C, Bäcklund M, Wengström Y, Borgquist S, Bergqvist J, Eriksson M, Tapia J, Czene K, Hall P. Side effects of low-dose tamoxifen: results from a six-armed randomised controlled trial in healthy women. Br J Cancer. 2023 Jul;129(1):61-71. doi: 10.1038/s41416-023-02293-z
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Garcia L, Pearce M, Abbas A, Mok A, Strain T, Ali S, Crippa A, Dempsey PC, Golubic R, Kelly P, Laird Y, McNamara E, Moore S, de Sa TH, Smith AD, Wijndaele K, Woodcock J, Brage S. Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies. Br J Sports Med. 2023 Feb 28:bjsports-2022-105669.
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Sachs MC, Gabriel EE, Crippa A, Daniels MJ. Flexible evaluation of surrogacy in platform studies. Biostatistics. 2023 Jan 4.
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Sabé M, Pallis K, Solmi M, Crippa A, Sentissi O, Kaiser S. Comparative Effects of 11 Antipsychotics on Weight Gain and Metabolic Function in Patients With Acute Schizophrenia: A Dose-Response Meta-Analysis. JThe Journal of Clinical Psychiatry. 2023 Feb 8;84(2):45463.
2022
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Files DC, Matthay MA, Calfee CS, Aggarwal NR, Asare AL, Beitler JR, Berger PA, Burnham EL, Cimino G, Coleman MH, Crippa A. I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations. BMJ open. 2022 Jun 1;12(6):e060664.
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Vigneswaran HT, Mittelstaedt L, Crippa A, Eklund M, Vidal A, Freedland SJ, Abern MR. Progression on active surveillance for prostate cancer in Black men: a systematic review and meta-analysis. Prostate Cancer and Prostatic Diseases. 2022 Jun;25(2):165-73.
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Mortezavi A, Crippa A, Kotopouli MI, Akre O, Wiklund P, Hosseini A. Association of Open vs Robot-Assisted Radical Cystectomy With Mortality and Perioperative Outcomes Among Patients With Bladder Cancer in Sweden. JAMA Netw Open. 2022;5(4):e228959.
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De Laere B, Crippa A, Discacciati A, Larsson B, Oldenburg J, Mortezavi A, Ost P, Eklund M, Lindberg J, Grönberg H. Clinical Trial Protocol for ProBio: An Outcome-adaptive and Randomised Multiarm Biomarker-driven Study in Patients with Metastatic Prostate Cancer. European Urology Focus. 2022 Mar 19.
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Calfee CS, Eklund M, Albertson TE, Auld S, Beitler JR, Berger PA, Burnham EL, Cobb NK, Crippa A, Daniel BM, Discacciati A. The I-SPY COVID Trial: First Results from an Adaptive Platform Phase 2 Trial for Severe COVID-19. InD94. PANDEMIC OUTPUT: ALL THAT IS COVID-19 2022 May (pp. A5284-A5284). American Thoracic Society.
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I-SPY COVID Consortium. Clinical trial design during and beyond the pandemic: the I-SPY COVID trial. Nature medicine.
2021
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Sabe, M., Zhao, N., Crippa A, Strauss, G.P. and Kaiser, S. Intranasal oxytocin for negative symptoms of schizophrenia: systematic review, meta-analysis and dose-response meta-analysis of randomized controlled trials.. International Journal of Neuropsychopharmacology. 2021.
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Eriksson, M., Eklund, M., Borgquist, S., Hellgren, R., Margolin, S., Thoren, L., ..., Crippa A, ..., Hall, P. Low-Dose Tamoxifen for Mammographic Density Reduction: A Randomized Controlled Trial. Journal of Clinical Oncology. 2021. pp.JCO-20
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De Laere, B., Crippa A, Mortezavi, A., Ghysel, C., Rajan, P., Eklund, M., Wyatt, A., Dirix, L., Ost, P., Grönberg, H. and Lindberg, J Increased Pathway Complexity Is a Prognostic Biomarker in Metastatic Castration-Resistant Prostate Cancer. Cancers, 2021. 13(7), p.1588
2020
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Mortezavi A, Crippa A, Edeling S, Pokupic S, Dell’Oglio P, Montorsi F, D'Hondt F, Mottrie A, Decaestecker K, Wijburg, CJ, Collins J, Kelly JD, Tan WS, Sridhar A, John H, Canda AE, Schwentner C, Rönmark EP, Wiklund P, Hosseini A. The Morbidity and mortality after robot‐assisted radical cystectomy with intracorporeal urinary diversion in octogenarians – results from the EAU Robotic Urology Section (ERUS) Scientific Working Group. BJU Int. Accepted Author Manuscript. doi:10.1111/bju.15274
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Crippa A, De Laere B, Discacciati A, et al. The ProBio Trial: Molecular Biomarkers for Advancing Personalized Treatment Decision in Patients With Metastatic Castration-Resistant Prostate Cancer. Trials. 2020;21(1):579. Published 2020 Jun 26. doi:10.1186/s13063-020-04515-8
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Lantz A, Haug ES, Picker W, Crippa A, Jäderling F, Mortezavi A, Nordström T. Effect of information on prostate biopsy history on biopsy outcomes in the era of MRI‑targeted biopsies. World Journal of Urology. 2020; doi:10.1007/s00345-020-03277-x
2019
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Leucht S, Crippa A, Siafis S, Patel MX, Orsini N, Davis JM. Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia. American Journal of Psychiatry. 2019 Dec 16:appi-jp.
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Zhou X, Crippa A, Danielsson A, Galanti M.R., Orsini N. Effect of tobacco control policies on the Swedish smoking quitline using intervention time-series analysis. BMJ Open 2019;9:e033650. doi: 10.1136/bmjopen-2019-033650
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Blond K, Brinkløv CF, Ried-Larsen M, Crippa A,, Grøntved A. Association of high amounts of physical activity with mortality risk: a systematic review and meta-analysis. British journal of sports medicine.. 2019 Aug 12:bjsports-2018.
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Filippini T, Hatch E.E., Rothman K.J., Heck J.E., Park A.S., Crippa A, Orsini N., Vinceti
M.. Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose–Response Meta-Analysis.. Environmental Health Perspectives. 2019.
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Crippa A, Discacciati A, Bottai M, Spiegelman D, Orsini N. One-stage dose-response meta-analysis for aggregated data.. Statistical Methods in Medical Research. 2019 May;28(5):1579-96.
2018
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Trevisan C, Crippa A, Ek S, Welmer AK, Sergi G, Maggi S, Manzato E, Bea JW, Cauley JA, Decullier E, Hirani V. Nutritional status, body mass index, and the risk of falls in community-dwelling older adults: a systematic review and meta-analysis.. Journal of the American Medical Directors Association. 2018 Dec 13.
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Brage S, Abbas A, Mok A, Garcia L, McNamara E, Crippa A, Sa T, Smith A, Kim D, Im J, Olayinka O. Non-occupational physical activity and risk of cardiovascular disease, cancer, and mortality: a dose-response meta-analysis of prospective studies.. Journal of Physical Activity and Health. 2018 Oct 1, Vol. 15, No. 10, pp. S36-S36.
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Lugo A, Peveri G, Bosetti C, Bagnardi V, Crippa A, Orsini N, Rota M, Gallus, S. Strong excess risk of pancreatic cancer for low frequency and duration of cigarette smoking: A comprehensive review and meta-analysis.. European Journal of Cancer. 2018 104, pp.117-126.
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Crippa A, Thomas I, Orsini N. A pointwise approach to dose-response meta-analysis of aggregated data. International Journal of Statistics in Medical Research. 2018 May 8;7(2):25-32.
2017
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Aneni EC, Crippa A, Osondu CU, Valero‐Elizondo J, Younus A, Nasir K, Veledar E. Estimates of Mortality Benefit From Ideal Cardiovascular Health Metrics: A Dose Response Meta-Analysis. Journal of the American Heart Association. 2017 Dec 1;6(12):e006904.
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Crippa A, Larsson SC, Discacciati A, Wolk A, Orsini N. Red and processed meat consumption and risk of bladder cancer: a dose-response meta-analysis of epidemiological studies. European Journal of Nutrition. 2017 Jan.
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Discacciati A, Crippa A, Orsini N. Goodness of fit tools for dose-response meta-analysis of binary outcomes. Research synthesis methods. 2017 Jun;8(2):149-60.
2016
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Smith AD, Crippa A, Woodcock J, Brage S. Total and leisure-time physical activity and incident type 2 diabetes mellitus: A systematic review and dose-response meta-analysis of prospective cohort studies. Diabetologia 2016, 59, 2527-2545
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Vinceti M, Filippini T, Crippa A, de Sesmaisons A, Wise LA, Orsini N. Meta‐Analysis of Potassium Intake and the Risk of Stroke. Journal of the American Heart Association. 2016 Oct 1;5(10):e004210.
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Crippa A, Orsini N. Multivariate Dose-Response Meta-Analysis: the dosresmeta R Package. Journal of Statistical Software, Code Snippets, 72(1), 1-15. doi:10.18637/jss.v072.c01.
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Veledar E, Crippa A, Osondua CU, Younusa A, Nasira K. Letter to editor: “Ideal cardiovascular health metrics and risk of cardiovascular disease or mortality: A meta-analysis”. International Journal of Cardiology. 2016 Nov 1.
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Crippa A, Orsini N. Dose-response meta-analysis of differences in means. BMC Medical Research Methodology. 2016 Aug 2;16(1):91.
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Crippa A, Khudyakov P, Wang M, Orsini N, Spiegelman D. A new measure of between-studies heterogeneity in meta-analysis. Statistics in Medicine. 2016 May 10. doi: 10.1002/sim.6980.
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Crippa A, Discacciati A, Orsini N, Oskarsson V. Letter: coffee consumption and gallstone disease - a cautionary note on the assignment of exposure values in dose-response meta-analyses. Alimentary pharmacology & therapeutics. 2016 Jan 1;43(1):166-7. doi: 10.1111/apt.13428.
2015
2014